Saitama Medical University · Faculty of Medicine / Graduate School of Medicine · 講師

Research keywordslong noncoding RNAs・FUS/TLS RNA-binding proteins・spermatogenesis・RNA methylation・gene activation in granulosa cells・cell cycle regulation・testis-specific serine proteases

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• Non-coding RNA suppresses FUS aggregation caused by mechanistic shear stress on pipetting in a sequence-dependent manner
• A genomic region transcribed into a long noncoding RNA interacts with the Prss42/Tessp-2 promoter in spermatocytes during mouse spermatogenesis, and its flanking sequences can function as enhancers.
• m6A Modified Short RNA Fragments Inhibit Cytoplasmic TLS/FUS Aggregation Induced by Hyperosmotic Stress
• Three testis-specific paralogous serine proteases play different roles in murine spermatogenesis and are involved in germ cell survival during meiosis.

• 2023/04～2026/03 ALS病因タンパク質FUSのm6A修飾認識タンパク質としての機能解析 基盤研究C2023 · 研究課題・受託研究・科研費
• 2017/04～2021/03 プロモーターから発現するlncRNAによるcyclin D1遺伝子の発現制御機構 若手研究(B)2017 · 研究課題・受託研究・科研費
• プロモーターから発現するlncRNAによるcyclin D1遺伝子の発現制御機構
• ALS病因タンパク質FUSのm6A修飾認識タンパク質としての機能解析

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