Setsunan University · Faculty of Pharmaceutical Sciences · 教授

Research keywordsstructural enzymology・aminopeptidase N・oligopeptidase B・crystal structure・substrate inhibition・bacterial peptidases・D-3-hydroxybutyrate dehydrogenase

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• Relationship among activation of the Na+/H+ antiporter, ornithine decarboxylase induction, and DNA synthesis
• Prolyl aminopeptidase is also present in Enterobacteriaceae: Cloning and sequencing of the Hafnia alvei enzyme-gene and characterization of the expressed enzyme
• Journal of Biochemistry171論文
• Expression and function of normal and LNCaP androgen receptors in androgen-insensitive human prostatic cancer cells

• 歯周病原性細菌における新規ペプチド分解機構の解明
• 小分子な蛍光性化合物の開発と歯周病菌の蛍光プローブ創製
• M1及びS9ファミリーに属する高分子量ペプチダーゼの構造解析
• トリパノソーマ及びマラリアの新規治療薬を目指したキーとなる酵素の構造解析

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