Setsunan University · Faculty of Pharmaceutical Sciences · 教授

Research keywords膜透過性・共結晶・吸収改善・溶解性・経口吸収・薬物代謝・薬物間相互作用・製剤・輸送担体・過飽和

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• An enteric polymer mitigates the effects of gastric pH on oral absorption of poorly soluble weak acid drugs from supersaturable formulations: A case study with dantrolene
• Multifunctional nanobeacon for imaging Thomsen-Friedenreich antigen-associated colorectal cancer.
• New methods to evaluate intestinal drug absorption mediated by oligopeptide transporter from in vitro study using Caco-2 cells.
• In Vivo Fluid Volume in Rat Gastrointestinal Tract: Kinetic Analysis on the Luminal Concentration of Nonabsorbable FITC-Dextran After Oral Administration.

• PETを用いた薬物体内動態研究
• 加齢や相互作用による消化管内生理条件変化に起因した薬物体内動態変化の抑制を指向 した新規経口吸収改善製剤コンセプトの確立
• 薬物の経口吸収性評価
• アンテドラッグとして作用する、安全で新規な薬物動態学的増強因子の創出

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