Shimane University · University Hospital

Research keywordsnon-small cell lung cancer・thoracic oncology・targeted therapy・immunotherapy biomarkers・extracellular vesicle biochip・geriatric chemotherapy

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• Selective targeting of GARP-LTGFβ axis in the tumor microenvironment augments PD-1 blockade via enhancing CD8+ T cell antitumor immunity.
• Chloroquine augments TRAIL-induced apoptosis and induces G2/M phase arrest in human pancreatic cancer cells.
• Prospective clinical trial evaluating vulnerability and chemotherapy risk using geriatric assessment tools in older patients with lung cancer.
• EGFR-TKIに耐性を示し再生検でT790M変異と小細胞癌への転化を認めた1例

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