Shimane University · Faculty of Medicine

Research keywords平滑筋収縮・細胞遊走・シグナル伝達

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• Calcium regulation of the ATPase activity of Physarum and scallop myosins using hybrid smooth muscle myosin: The role of the essential light chain
• Paxillin controls actin stress fiber formation and migration of vascular smooth muscle cells by directly binding to the active Fyn.
• Hesperetin inhibits sphingosylphosphorylcholine-induced vascular smooth muscle contraction by regulating the Fyn/Rho-kinase pathway.
• Effect of Paxillin Expression and Phosphorylation on Colorectal Cancer Prognosis and Metastasis.

• 中間径フィラメントビメンチンを介した新規血管平滑筋異常収縮シグナル伝達機構の解明
• 新規に同定した細胞接着斑分子paxillinが血管攣縮における役割の解明
• 新規に同定した細胞接着斑分子paxillinが血管攣縮を制御するメカニズムの解明
• 細胞骨格制御の観点から難病疾患群に共通する病的シグナル伝達系を解明する

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