Shimane University · Faculty of Medicine · 教授

Research keywords糖尿病・bone metabolism・Diabetes mellitus・Endocrinology・内分泌代謝・骨代謝・骨粗鬆症

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• Decreased PTH levels accompanied by low bone formation are associated with vertebral fractures in postmenopausal women with type 2 diabetes.
• Adiponectin and AMP kinase activator stimulate proliferation, differentiation, and mineralization of osteoblastic MC3T3-E1 cells.
• Stimulating effect of erythropoietin on the release of dopamine and acetylcholine from the rat brain slice
• Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes.

• 新規海綿骨構造指標と有限要素法を活用した２型糖尿病の構造的骨質低下機序の解明
• サルコペニアに着眼した２型糖尿病の骨形状劣化に対する新規骨質評価法の開発
• AGEs-RAGE系とFetuin-Aの骨代謝と動脈硬化に対する病態生理の解明
• 低酸素ストレスと脂肪化筋喪失・骨構造劣化：２型糖尿病の新たな骨脆弱性機序の探求

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