Shimane University · University Hospital

Research keywords代謝・糖尿病・老化・肥満・脂肪細胞・腎臓

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• Percutaneous muscle biopsy-induced tissue injury causes local endoplasmic reticulum stress.
• Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice.
• NAMPT-Mediated NAD(+) Biosynthesis Is Essential for Vision In Mice.
• NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR.

• Identification of novel blood biomarkers and mediators of obesity-induced insulin resistance
• NAD合成系-Sirt1を標的とした2型糖尿病への新しいトランスレーショナル型リサーチの展開
• 脂肪細胞ミトコンドリアNAD代謝を標的とした2型糖尿病・インスリン抵抗性新規治療法の開発
• Regulation of systemic glucose and lipid homeostasis by adipocyte NAD biosynthesis

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