Shinshu University · Department of Medicine / Faculty of Medicine · 准教授

Research keywordsoxidized LDL・LOX-1 receptor・atherogenic lipoproteins・adiponectin-LDL complexes・coronary thrombosis・soluble LOX-1・coronary artery disease・SARS-CoV-2 coagulopathy・scavenger receptor signaling・radioiodinated oxLDL imaging

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• LOX-1 ligands containing apolipoprotein B and carotid intima-media thickness in middle-aged community-dwelling US Caucasian and Japanese men.
• Lectin-like oxidized LDL receptor 1 is involved in CRP-mediated complement activation.
• Lectin-like oxidized low-density lipoprotein receptor 1 signal is a potent biomarker and therapeutic target for human rheumatoid arthritis.
• Quantitative and qualitative lipid improvement with chronic hepatitis C virus eradication using with direct‐acting antivirals

• 播種性血管内凝固症候群の病態基盤としての内皮機能異常とLOX-1の意義の解明
• 肺高血圧症病態生理における血管内皮機能分子の意義の解明
• 血管機能異常による高脂肪食依存性機構の解明
• 高尿酸血症から痛風発作に至る生体分子機構の研究

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