Shinshu University · Shinshu Cancer Center · 講師

Research keywords消化器外科・臨床腫瘍学・肝胆膵癌・腹腔鏡手術・抗体療法

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• Two Distinct Mechanisms of Augmented Antitumor Activity by Modulation of Immunostimulatory/Inhibitory Signals
• CCR4-positive peripheral T-cell lymphoma presenting as eosinophilic pneumonia and developing from prolonged pustular psoriasis.
• Newly emerged immunogenic neoantigens in established tumors enable hosts to regain immunosurveillance in a T-cell-dependent manner.
• EGFR inhibition in EGFR-mutant lung cancer cells perturbs innate immune signaling pathways in the tumor microenvironment.

• 宿主免疫抑制性分子を標的とした新規肺癌免疫療法の開発
• 肺癌免疫療法におけるメモリー型T細胞・樹状細胞クロストークの解明
• 非小細胞肺癌に対するシアロ糖タンパク質を標的とした新規がん免疫治療の開発
• 肺癌に対するメモリー型抗腫瘍T細胞誘導治療薬の開発

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