Shinshu University · Department of Medicine / Faculty of Medicine · 特任准教授

Research keywordsprimary immunodeficiency・common variable immunodeficiency・Kawasaki disease biomarkers・juvenile systemic lupus erythematosus・ocular myasthenia gravis・interstitial lung disease genetics・memory B cells

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• Markedly elevated CD64 expression on neutrophils and monocytes as a biomarker for diagnosis and therapy assessment in Kawasaki disease
• Polarization of Th1/Th2 in human CD4+ T cells separated by CD62L: analysis by transcription factors
• IL-18 serum concentration is markedly elevated in typical familial Mediterranean fever with M694I mutation and can distinguish it from atypical type
• Novel Artemis gene mutations of radiosensitive severe combined immunodeficiency in Japanese families

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