Shinshu University · Department of Medicine / Faculty of Medicine · 助教

Research keywordshepatocellular carcinoma・gastric cancer・pim-3 kinase・molecular pathology・tumor biomarkers・cancer progression

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• Aberrant Pim-3 expression is involved in gastric adenoma-adenocarcinoma sequence and cancer progression.
• Novel role of ASC as a regulator of metastatic phenotype.
• Blocking TNF-a in mice reduces colorectal carcinogenesis associated with chronic colitis.
• Spontaneous regression of lung metastasis in the absence of tumor necrosis factor receptor p55.

• 新規素材カーボンナノチューブの毒性および発がん性評価
• インフラマソーム構成分子ASCによるがん細胞の転移制御機構の解明
• 胃腺粘液特異的糖鎖を指標とした予後不良分化型胃がんの診断・治療法開発
• アダプタータンパク質ASC下流シグナルを標的とした新規大腸がん治療標的分子の同定

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