Shinshu University · University Hospital · 助教

Research keywordsendometrial carcinoma・gynecologic oncology・ovarian clear cell carcinoma・oncogene screening・progesterone receptor・tumor microenvironment・cervical adenocarcinoma・vasa previa

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• Lipocalin2 enhances the matrix metalloproteinase-9 activity and invasion of extravillous trophoblasts under hypoxia
• Ligand-Based CAR-T Cells Targeting EGFR Exhibit Favorable Antitumor Effects Against Gynecologic Malignancies.
• Mutation analysis by whole exome sequencing of endometrial hyperplasia and carcinoma in one patient: Abnormalities of polymerase epsilon and the phosphatidylinositol-3 kinase pathway.
• Immunohistochemical detection of a specific receptor for lipocalin2 (solute carrier family 22 member 17, SLC22A17) and its prognostic significance in endometrial carcinoma

• マウスモデルを用いた子宮内膜症関連卵巣癌発癌メカニズムの検討
• サイクリンAを標的とした子宮内膜癌治療薬の開発：新規化合物の機能解析と改良
• 子宮頸部胃型腺癌の実験モデルの開発と薬剤感受性の検討
• 子宮内膜癌に対する抗サイクリンA分子標的薬開発：新たに同定した化合物の改良の試み

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