Shinshu University · Organization for Academic Research and Industry-Academia-Government Collaboration Promotion · 特任教授

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• OBP‑801, a novel histone deacetylase inhibitor, induces M‑phase arrest and apoptosis in rhabdomyosarcoma cells.
• Biological characteristics of the leukemia-associated transcriptional factor AML1 disclosed by hematopoietic rescue of AML1-deficient embryonic stem cells by using a knock-in strategy
• Targeting FLT3-specific chimeric antigen receptor T cells for acute lymphoblastic leukemia with KMT2A rearrangement.
• [Successful treatment with pseudo-autologous blood stem cell transplantation for an adolescent-onset multiple myeloma who relapsed after allogenic bone marrow transplantation].

• 神経芽腫に対する間葉系間質細胞を用いた遺伝子細胞治療法の開発
• EPHB4受容体陽性悪性軟部腫瘍を標的とした非ウイルス遺伝子改変キメラ抗原受容体T細胞療法の非臨床試験
• 横紋筋肉腫に対する新規遺伝子治療の開発
• 小児がんに対するキメラ抗原受容体T細胞を用いた細胞製剤の開発

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