Shizuoka University · Graduate School of Education / Faculty of Education · 准教授

Research keywordsosteoclasts・Pleurodeles waltl・Xenopus tropicalis・アフリカツメガエル・イベリアトゲイモリ・ゲノム編集・ケモカイン・培養細胞

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• Ubc9 negatively regulates BMP-mediated osteoblastic differentiation in cultured cells
• Localization of SUMOylation factors and Osterix in odontoblast lineage cells during dentin formation and regeneration
• Novel Daple-like protein positively regulates both the Wnt/beta-catenin pathway and the Wnt/JNK pathway in Xenopus
• Xldax, an inhibitor of the canonical Wnt pathway, is required for anterior neural structure formation in Xenopus

• SUMO化修飾の阻害による骨芽細胞分化促進機構の解明
• SUMO化修飾の調節による歯根膜細胞から骨芽細胞への分化制御
• 遺伝子改変両生類を用いた新たな骨リモデリング機序の解析方法の確立
• 遺伝子改変両生類を用いた新たな骨代謝分子機構の探索

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