Shonan University of Medical Sciences · Faculty of Pharmacy · 教授

Research keywords感染免疫・薬剤耐性・病原性

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• Efficacies of calcium-EDTA in combination with imipenem in a murine model of sepsis caused by Escherichia coli with NDM-1 β-lactamase.
• In Vitro Intracellular Activity and In Vivo Efficacy of Modithromycin, a Novel Bicyclolide, against Legionella pneumophila
• Roles of Pseudomonas aeruginosa Autoinducers and their Degradation Products, Tetramic acids, in Bacterial Survival and Behavior in Ecological Niches
• Use of culture-independent analysis to reveal alteration of intestinal microflora by heat-killed Lactobacillus pentosus in a mouse model of endogenous sepsis

• 肺炎球菌性肺炎の重症化に関わる疾患感受性遺伝子の同定とその機能解析
• CTX-M型ラクタマーゼのセフタジジム分解性における167番目のアミノ酸変異の役割
• 細菌性肺炎の自然免疫に関わる各種T細胞の挙動および免疫終息因子に関する研究
• 腸上皮細胞による腸内細菌叢の調節と免疫恒 常性の維持機構

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