Shonan University of Medical Sciences · Faculty of Pharmacy · 教授

Research keywordsmedicinal chemistry・natural products・antiplasmodial compounds・trypanocidal activity・chemoresistance・quantum chemical calculations

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• Downregulation of claudin-2 expression and chemoresistance by saquinavir in human lung adenocarcinoma cells2026
• Nemophilosides A–I, nine meroterpenoid glucosides isolated from Nemophila menziesii2026
• Isolation of sesquiterpenoids and trypanocidal constituents from Artemisia adamsii2025
• Isolation of Antiplasmodial Oxazoles and Isoflavonoids from the Roots of Oxytropis trichophysa and Total Synthesis of Oxazole-type Alkaloids.2025

• AS-MSによるPD-1ーPD-L1低分子阻害剤の探索2024
• DNA修復特性を用いたがん治療耐性に対する制御機構の解明2023
• 新規抗がん剤開発を目指すtRNA修飾酵素と阻害化合物の構造活性相関解明2022
• 膠芽腫幹細胞を標的としたtRNAメチル化酵素阻害剤による制がん戦略の構築2020

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