Showa Pharmaceutical University · Microbiology Laboratory

Research keywordsherpesvirus ubiquitin ligases・Kaposi sarcoma-associated herpesvirus・substrate recognition・L-selectin downregulation・antiviral compounds・lignosulfonate・herpes simplex virus・HIV inactivation

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• Importance of accessibility to the extracellular juxtamembrane stalk region of membrane protein for substrate recognition by viral ubiquitin ligase K5 Kajikawa M, Hata M, Ishimura M, Imaizumi N, Kimura M, Miyano K, Ose T, Asai D, Ishido S, Kanamoto T. Biochem J 479 2261-2278 20222022
• Re-Evaluation of Chemotherapeutic Potential of Pyoktanin Blue. Sakagami H, Furukawa T, Satoh K, Amano S, Iijima Y, Koshikawa T, Asai D, Fukuchi K, Takemura H, Kanamoto T, Yokose S. Medicines (Basel) 8 33 20212021
• Lignosulfonate Rapidly Inactivates Human Immunodeficiency and Herpes Simplex Viruses. Fukuchi K, Koshikawa T, Asai D, Inomata M, Sakagami H, Takemura H, Kanamoto T, Aimi H, Kikkawa Y. Medicines (Basel) 8 56 20212021
• Kaposi's sarcoma-associated herpesvirus ubiquitin ligases downregulate cell surface expression of l-selectin. Kajikawa M, Imaizumi N, Machii S, Nakamura T, Harigane N, Kimura M, Miyano K, Ishido S, Kanamoto T J Gen Virol 102 20212021

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