St. Marianna University School of Medicine · School of Medicine · 准教授

Research keywordsprimary aldosteronism・adrenalectomy・aldosterone biosynthesis・mineralocorticoid receptor・adrenal embolization・Cushing syndrome・circadian sodium handling

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• Case Report: Nodule Development From Subcapsular Aldosterone-Producing Cell Clusters Causes Hyperaldosteronism.
• CASZ1b is a novel transcriptional corepressor of mineralocorticoid receptor.
• Regulation of differential COUP-TF-coregulator interactions in adrenal cortical steroidogenesis.
• [Endocrine and Metabolic Emergencies; Points of Initial Management. Editorial: Endocrine and metabolic emergencies].

• 概日リズムによるMR活性化と高血圧発症機構の解明
• 高血圧・原発性アルドステロン症発症におけるCASZ1の疾患感受性SNPの役割の解明
• アルドステロン作用におけるミネラルコルチコイド受容体のSUMO化修飾の役割
• 新規MR転写共役因子CASZ1による高血圧発症メカニズムの解明

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