St. Marianna University School of Medicine · School of Medicine · 教授

Research keywords自己免疫疾患・リウマチ性疾患・プロテオミクス・Autoimmunity・血清ペプチド・ANCA関連血管炎・シェドミクス

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• Peroxiredoxin 2 is a novel autoantigen for anti-endothelial cell antibodies in systemic vasculitis
• Secretion of inflammatory factors from chondrocytes by layilin signaling
• The attenuation of insulin-like growth factor signaling may be responsible for relative reduction in matrix synthesis in degenerated areas of osteoarthritic cartilage.
• Role of layilin in regulating mitochondria-mediated apoptosis: a study on B cell lymphoma (BCL)-2 family proteins.

• 自己抗体産生機序の解明
• 自己免疫疾患に関わる細胞のプロテオーム解析
• 翻訳後修飾アセチル化に着目した「新規関節リウマチ検査」の確立
• Study on the mechanisms for autoantibody production

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