Suzuka University of Medical Science · Faculty of Pharmaceutical Sciences / Graduate School of Pharmaceutical Sciences · 助教

Research keywordsadvanced glycation end products・beta-tubulin aggregation・neurite outgrowth・optic nerve degeneration・neuroblastoma cells・temporal lobe epilepsy proteomics・intracellular TAGE

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• Toxic Advanced Glycation End-Products Inhibit Axonal Elongation Mediated by β-Tubulin Aggregation in Mice Optic Nerves.2024 · International Journal of Molecular Sciences.
• Pyridoxamine and aminoguanidine attenuate the abnormal aggregation of β-tubulin and suppression of neurite outgrowth by glyceraldehyde-derived toxic advanced glycation end-products.2022 · Frontiers in Pharmacology.
• 毒性終末糖化産物（TAGE）による中枢神経軸索形成阻害に対するピリドキサミンの抑制効果.2022 · ビタミン
• Intracellular Toxic AGEs (TAGE) Triggers Numerous Types of Cell Damage.2021 · Biomolecules.

• 損傷後視神経における神経－グリア連関による新規再生メカニズムの解析
• 筋萎縮性側索硬化症(ALS)における酸化ストレスの役割解明と新規治療標的分子の探索
• 低酸素性虚血性脳症の治療標的としての酸化損傷タンパク質を 探る機能プロテオミクス
• ヒトてんかん原性脳組織における酸化損傷タンパク質の網羅的探索 と細胞毒性の解析

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