Teikyo University · Faculty of Pharmaceutical Sciences · 講師

Research keywords神経変性疾患・うつ病・神経薬理・神経成長因子・シグマ受容体

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• Estimation of Interindividual Variability of Pharmacokinetics of CYP2C9 Substrates in Humans.
• The Kampo medicine Yokukansan (YKS) enhances nerve growth factor (NGF)-induced neurite outgrowth in PC12 cells.
• Relationship between the acyl chain length of paradol analogues and their antiobesity activity following oral ingestion.
• Fluvoxamine moderates reduced voluntary activity following chronic dexamethasone infusion in mice via recovery of BDNF signal cascades.

• ステロイド誘起性うつ病における病態実験モデル構築と治療薬の提案
• 血管透過性亢進に起因するボルテゾミブ誘発性肺障害の発症機序解明
• 子宮頸がんの放射線治療に対する耐性形成の検証と克服戦略
• XDH欠損による高ヒポキサンチン状態が脳内に及ぼす影響の解析

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