Teikyo University · Faculty of Pharmaceutical Sciences · 講師

Research keywords臨床薬物動態学・グミ製剤・pharmacokinetics・pharmacodynamics・薬物動態学・臨床製剤学

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• Effect of rifampicin and clarithromycin on the CYP3A activity in patients with Mycobacterium avium complex.
• Development of simultaneous determination of dopamine 2, histamine 1, and muscarinic acetylcholine receptor occupancies by antipsychotics using liquid chromatography with tandem mass spectrometry.
• Simultaneous and comprehensive in vivo analysis of cytochrome P450 activity by using a cocktail approach in rats.
• Quantitation of chafurosides A and B in tea leaves and isolation of prechafurosides A and B from oolong tea leaves.

• 薬剤性認知症回避を目指した抗コリン薬の新規リスク指標開発
• 小児患者のアドヒアランス向上を目的としたグミ製剤の開発
• 薬物相互作用の迅速・網羅的検出を目的とした基礎及び臨床カクテル試験の確立と応用
• 口腔内崩壊錠の服用性評価のための試験法確立とその応用

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