Teikyo University · Faculty of Pharmaceutical Sciences

Research keywordssphingomyelin synthase・glucosylceramide synthase・phospholipase A・acyltransferases・organelle dynamics・phosphoinositide signaling・GPR55 signaling・cow milk allergens・IgE epitopes・peptide arrays

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• Development of peptide arrays for detection of IgE-binding epitopes in cow's milk allergens
• Peptide array-based analysis of the specific IgE and IgG4 in cow's milk allergens and its use in allergy evaluation
• Implication of phospholipase D2 in oxidant-induced phosphoinositide 3-kinase signaling via Pyk2 activation in PC12 cells
• Coenzyme-A-Independent Transacylation System; Possible Involvement of Phospholipase A2 in Transacylation.

• 細胞内ホスホリパーゼA1の新しい機能の探索と病態への関与
• 微生物のゲノム配列解析による病原性と有用遺伝子システムの解明
• 脂質・鉄代謝異常の変化に着目した神経変性疾患の新規病態発症メカニズムの解明
• 細胞内ホスホリパーゼA1の“ワールブルグ効果”の解除と制がんへの応用

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