Institute of Science Tokyo · Graduate School of Medical and Dental Sciences

Research keywordsreplication stress・PARP inhibition・ATR vulnerability・SMARCA4-deficient cells・genomic instability

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• Kimiyoshi Yano, Megumi Kato, Syoju Endo, Taichi Igarashi, Ryoga Wada, Takashi Kohno, Astrid Zimmermann, Heike Dahmen, Frank T Zenke, Bunsyo Shiotani. PARP inhibition-associated heterochromatin confers increased DNA replication stress and vulnerability to ATR inhibition in SMARCA4-deficient cells. Cell Death Discovery. 2025.01; 11 (1): 31.2025
• Taichi Igarashi, Kimiyoshi Yano, Syoju Endo, Bunsyo Shiotani. Tolerance of Oncogene-Induced Replication Stress: A Fuel for Genomic Instability. Cancers (Basel). 2024.10; 16 (20): 3507.2024

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