Institute of Science Tokyo · Graduate School of Medical and Dental Sciences

Research keywords核酸医薬・アンチセンスオリゴヌクレオチド・神経筋疾患・神経毒性・カルシウム動態

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• Taiki Matsubayashi, Kotaro Yoshioka, Su Su Lei Mon, Maho Katsuyama, Chunyan Jia, Takao Yamaguchi, Rintaro Iwata Hara, Tetsuya Nagata, Osamu Nakagawa, Satoshi Obika, Takanori Yokota. Favorable efficacy and reduced acute neurotoxicity by antisense oligonucleotides with 2′,4′-BNA/LNA with 9-(aminoethoxy)phenoxazine Mol Ther Nucleic Acids. 2024.03;2024
• 神経・筋疾患を標的とした核酸医薬の基礎と臨床 神経治療学. 2023; 40 (3): 237-241.2023
• Chunyan Jia, Su Su Lei Mon, Ying Yang, Maho Katsuyama, Kie Yoshida-Tanaka, Tetsuya Nagata, Kotaro Yoshioka, Takanori Yokota. Change of intracellular calcium level causes acute neurotoxicity by antisense oligonucleotides via CSF route Molecular Therapy Nucleic Acids. 2023.03;2023
• Yohei Kawano, Maki Obana, Masashi Nagata, Yasunari Mano, Maho Katsuyama, Yuichiro Yamamoto, Ayako Maeda-Minami, Kenichi Negishi, Masamichi Takagi, Shuji Shimada, Takao Aoyama. The antiplatelet effect of mirtazapine is mediated by co-blocking 5-HT2A and α2-adrenergic receptors on platelets: An in vitro human plasma-based study Eur J Pharmacol. 2022.02; 917 174640. ( PubMed , DOI )2022

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