Institute of Science Tokyo · Graduate School of Medical and Dental Sciences

Research keywordsbrown adipose tissue thermogenesis・prediabetes screening・single-lead electrocardiograms・adipocyte progenitor cells・aldosterone-producing adenoma・extracellular vesicle microRNAs

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• Masato Horino, Kenji Ikeda, Rei Okazaki, Yujiro Nakano, Ryo Kaneda, Ryoko Ishii, Jun Aoki, Kazunari Hara, Akira Takeuchi, Yoshihiro Niitsu, Kuniyuki Taguchi, Kuniyuki Kano, Masanori Murakami, Kazutaka Tsujimoto, Chikara Komiya, Tetsuya Yamada. Car4-positive adipocyte progenitor cells adapt to the aging environment and work as protection against ROS via glutathione metabolism. Sci Rep. 2025.08; 15 (1): 31922. ( PubMed , DOI )2025
• Daisuke Koga, Ryo Kaneda, Chikara Komiya, Satoshi Ohno, Akira Takeuchi, Kazunari Hara, Masato Horino, Jun Aoki, Rei Okazaki, Ryoko Ishii, Masanori Murakami, Kazutaka Tsujimoto, Kenji Ikeda, Hideki Katagiri, Hideyuki Shimizu, Tetsuya Yamada. Artificial intelligence identifies individuals with prediabetes using single-lead electrocardiograms. Cardiovasc Diabetol. 2025.11; 24 (1): 415. ( PubMed , DOI )2025
• Akira Takeuchi, Kazutaka Tsujimoto, Jun Aoki, Kenji Ikeda, Nozomu Kono, Kuniyuki Kano, Yoshihiro Niitsu, Masato Horino, Kazunari Hara, Rei Okazaki, Ryo Kaneda, Masanori Murakami, Kumiko Shiba, Chikara Komiya, Junken Aoki, Tetsuya Yamada. Sex difference in BAT thermogenesis depends on PGC-1α-mediated phospholipid synthesis in mice. Nat Commun. 2025.07; 16 (1): 6072. ( PubMed , DOI )2025
• Masanori Murakami, Kazunari Hara, Kenji Ikeda, Masato Horino, Rei Okazaki, Yoshihiro Niitsu, Akira Takeuchi, Jun Aoki, Kumiko Shiba, Kazutaka Tsujimoto, Chikara Komiya, Yuki Nakamura, Morito Kurata, Takumi Akashi, Yasuhisa Fujii, Tetsuya Yamada. Single-Nucleus Analysis Reveals Tumor Heterogeneity of Aldosterone-Producing Adenoma. Hypertension. 2024.02; 81 (2): 361-371. ( PubMed , DOI )2024

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