Institute of Science Tokyo · Graduate School of Medical and Dental Sciences

Research keywordsParkinson disease protein DJ-1・glycolysis side product degradation・esterase activity・evolutionary trace analysis・protein biochemistry

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• Aiko Watanabe, Shizuka Ogiwara, Mirei Saito, Masaki Mishima, Masahiro Yamashina, Ryuichiro Ishitani, Yutaka Ito, Keiji Tanaka, Fumika Koyano, Koji Yamano, Hidetaka Kosako, Yoshitaka Moriwaki, and Noriyuki Matsuda. The reaction mechanism for glycolysis side product degradation by Parkinson’s disease–linked DJ-1 Journal of Cell Biology. 2025.08; ( PubMed , DOI )2025
• Aiko Watanabe, Fumika Koyano, Kenichiro Imai, Yohei Hizukuri, Shizuka Ogiwara, Tomoya Ito, Jun Miyamoto, Chihiro Shibuya, Mayumi Kimura, Kazuya Toriumi, Chie Motono, Makoto Arai, Keiji Tanaka, Yoshinori Akiyama, Koji Yamano, Noriyuki Matsuda. The origin of esterase activity of Parkinson's disease causative factor DJ-1 implied by evolutionary trace analysis of its prokaryotic homolog HchA. Journal of Biological Chemistry. 2024.07; ( PubMed , DOI )2024

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