Institute of Science Tokyo · Graduate School of Medical and Dental Sciences

Research keywordsdental pulp stem cells・odonto-osteoblastic differentiation・hypoxia-inducible factor 1 alpha・VEGFA signaling・mineral trioxide aggregate・inflammatory cytokines・endodontic biomaterials

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• Nyein Chan KO, Sonoko NODA, Yamato OKADA, Kento TAZAWA, Nobuyuki KAWASHIMA and Takashi OKIJI. Biocompatibility and pro-mineralization effects of premixed calcium silicatebased materials on human dental pulp stem cells: An in vitro and in vivo study Dental Materials Journal. 2024.09; 43 (5): 729-737.2024
• Alchawoosh A, Hashimoto K, Kawashima N, Noda S, Nozaki K, Okiji T. Hydraulic calcium silicate-based root canal sealers mitigate proinflammatory cytokine synthesis and promote osteogenesis in vitro Journal of Dental Sciences. 2023; ( DOI )2023
• Orikasa S, Kawashima N, Tazawa K, Hashimoto K, Sunada-Nara K, Noda S, Fujii M, Akiyama T, Okiji T. Hypoxia-inducible factor 1α induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/β-catenin transcriptional cofactor BCL9 Scientific Reports. 2022.01; 12 (682):2022
• Kieu TQ, Tazawa K, Kawashima N, Noda S, Fujii M, Nara K, Hashimoto K, Han P, Okiji T. Kinetics of LYVE-1-positive M2-like macrophages in developing and repairing dental pulp in vivo and their pro-angiogenic activity in vitro. Scientific reports. 2022.03; 12 (1): 5176. ( PubMed , DOI )2022

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