Meijo University · Faculty of Pharmaceutical Sciences · 教授

Research keywordsbehavioral pharmacology・memory impairment・dopamine systems・brain microdialysis・PCP analogs・stress neurochemistry

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• Phencyclidine-induced stereotyped behaviors after injection of ethylketocyclazocine, Mr 2266 and naltrexone in rats
• Potentiation of phencyclidine-induced stereotyped behaviors in rats by thiorphan and bestatin
• Pharmacological characterization of the ameliorating effect on learning and memory impairment and antinociceptive effect of KT-95 in mice
• Effects of nocistatin on nociceptin-induced impairment of learning and memory in mice

• オピオイドペプチド・ダイノルフィンAによるアルツハイマー型老年性痴呆薬の開発研究
• 脳内神経ペプチド・ノシセプチン類による学習・記憶調節に関与する脳内物質の同定
• ベタインによる認知症発症予防に向けた基礎的研究
• 神経発達過程におけるストレス負荷後の情動障害の発症脆弱に関わる機序解明と治療戦略

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