Tohoku University · Institute of Multidisciplinary Research for Advanced Materials

Research keywordsprotein crystallization・cell-free crystallization・serial femtosecond crystallography・protein crystal engineering・nanocrystal structure determination・intrinsically disordered proteins・porous protein crystals・cascade reactions

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• Cell-Free Protein Crystallization Enables Rapid Structure Determination of Disaccharides and Trisaccharides Using Galectin-10 CrystalsMariko Kojima, Xinchen Yao, Satoshi Abe, Tadaomi Furuta, Kunio Hirata, Ririko Kobayashi, Taiga Suzuki, Takafumi Ueno
• In-Cell Engineering of Protein Crystals with Nanoporous Structures for Promoting Cascade ReactionsTien K. Nguyen, Satoshi Abe, Makoto Kasamatsu, Basudev Maity, Keitaro Yamashita, Kunio Hirata, Mariko Kojima, Takafumi Ueno
• Engineering of an in-cell protein crystal for fastening a metastable conformation of a target miniproteinMariko Kojima, Satoshi Abe, Tadaomi Furuta, Duy Phuoc Tran, Kunio Hirata, Keitaro Yamashita, Yuki Hishikawa, Akio Kitao, Takafumi Ueno
• Crystal structure of the in-cell Cry1Aa purified from Bacillus thuringiensis.Tanaka J, Abe S, Hayakawa T, Kojima M, Keitaro Yamashita, Hirata K, Ueno T

• 天然多糖類分解酵素のin silico設計による糖転移酵素の構築小島摩利子
• タンパク質N末端修飾を利用した組織ターゲティングRNA医薬の開発小島 摩利子

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