Tohoku University · Tohoku Medical Megabank Organization

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• 3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome.Shu Tadaka, Fumiki Katsuoka, Masao Ueki, Kaname Kojima, Satoshi Makino, Sakae Saito, Akihito Otsuki, Chinatsu Gocho, Mika Sakurai-Yageta, Inaho Danjoh, Ikuko N Motoike, Yumi Yamaguchi-Kabata, Matsuyuki Shirota, Seizo Koshiba, Masao Nagasaki, Naoko Minegishi, Atsushi Hozawa, Shinichi Kuriyama, Atsushi Shimizu, Jun Yasuda, Nobuo Fuse, Gen Tamiya, Masayuki Yamamoto, Kengo Kinoshita
• The Il6 -39 kb enhancer containing clustered GATA2- and PU.1-binding sites is essential for Il6 expression in murine mast cells.Shin'ya Ohmori, Jun Takai, Satoshi Uemura, Akihito Otsuki, Tetsuya Mori, Kinuko Ohneda, Takashi Moriguchi
• Specific cancer types and prognosis in patients with variations in the KEAP1‐NRF2 system: A retrospective cohort studyTomoyuki Iwasaki, Hidekazu Shirota, Keiju Sasaki, Kota Ouchi, Yuki Nakayama, Hiroyuki Oshikiri, Akihito Otsuki, Takafumi Suzuki, Masayuki Yamamoto, Chikashi Ishioka
• ibSLS: A Biobank for Democratizing Access to Multi-Omics Data and Biospecimens from Spaceflight ResearchAkihito Otsuki, Yuichi Aoki, Risa Okada, Daisuke Kamimura, Dai Shiba, Eiji Hishinuma, Seizo Koshiba, Fumiki Katsuoka, Kengo Kinoshita, Takafumi Suzuki, Akira Uruno, Masayuki Yamamoto

• NRF2標的遺伝子の活性化に基づく疾患リスク層別化法の開発山本雅之、大槻晃史、日高高徳
• 全長トランスクリプトーム解析を基盤としたNRF2活性化がんの悪性化機構と治療標的探索大槻 晃史
• sMaf転写因子を中心とした遺伝子発現制御ネットワークの解明大槻 晃史
• Nrf2と小Maf二量体による協調的な生体防御遺伝子発現制御の解明大槻 晃史

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