Tohoku University · Institute of Multidisciplinary Research for Advanced Materials

Research keywordsAnticancer Drug Delivery・Nano-Prodrugs・Cancer Nanomedicine・SN-38 Conjugates・Stimuli-Responsive Therapeutics・Prodrug Design

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• Anticancer nano-prodrugs with drug release triggered by intracellular dissolution and hydrogen peroxide responseAki Shibata, Yoshitaka Koseki, Keita Tanita, Showa Kitajima, Kouki Oka, Kiyotaka Maruoka, Ryuju Suzuki, Anh Thi Ngoc Dao, Hitoshi Kasai
• Cytotoxicity Study of π-Conjugated Arsenic CompoundsTomoki Yasui, Aki Shibata, Tomoka Ishikawa, Yukako Fujita, Chihiro Okochi, Yoshitaka Koseki, Hitoshi Kasai, Kouki Oka, Kensuke Naka, Hiroaki Imoto
• Fabrication of carrier-free heterodimeric nano-prodrugs with podophyllotoxin and SN-38 for a co-delivery systemYoshitaka Koseki, Keita Tanita, Motofumi Nakamura, Aki Shibata, Kiyotaka Maruoka, Takaaki Kamishima, Hitoshi Kasai
• SN-38-indoximod conjugate: carrier free nano-prodrug for cancer therapySanjay Kumar, Yoshitaka Koseki, Keita Tanita, Aki Shibata, Asuka Mizutani, Hitoshi Kasai

• 水中の難分解性フッ化物を可視光分解できる有機ナノ粒子の創製柴田 暁貴
• がん細胞内でのみ薬物を放出するプロドラッグナノ粒子の創製柴田 暁貴

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