Tohoku Medical and Pharmaceutical University · Unclassified · 教授

Research keywordsbacterial pathogenesis・Salmonella・type III secretion system・Chromobacterium・virulence factors・Escherichia coli・gut infection・proteomics

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• Intestinal luminal polyamines support the gut colonization of enteric bacterial pathogens by modulating flagellar motility and nitrate respiration.
• Interplay between MgtC and PagC in Salmonella enterica serovar Typhimurium.
• Characterization of Salmonella pathogenicity island 1 type III secretion-dependent hemolytic activity in Salmonella enterica serovar Typhimurium.
• O-acetylesterase activity of Bifidobacterium bifidum sialidase facilities the liberation of sialic acid and encourages the proliferation of sialic acid scavenging Bifidobacterium breve.

• 抗菌レクチンに依存した腸内細菌による感染制御機構の解明
• 細菌性腸炎における抗菌性レクチンの役割の解明
• 脂肪酸の代謝と遺伝子発現制御によるサルモネラ病原性発現機構の解析
• 離島地域におけるブロードバンド整備の地域的影響に関する総合的研究

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