Tohoku Medical and Pharmaceutical University · Graduate School of Pharmaceutical Sciences · 教授

Research keywordsがん転移•浸潤・細胞シグナル伝達・膜受容体・細胞接着・増殖・移動・脳神経機能・糖タンパク質糖鎖・固形ガンと血液ガン

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• BRCC36 associates with FLT3-ITD to regulate its protein stability and intracellular signaling in acute myeloid leukemia.
• Deletion of core fucosylation on alpha3beta1 integrin down-regulates its functions.
• Branched N-glycans regulate the biological functions of integrins and cadherins.
• E-cadherin and adherens-junctions stability in gastric carcinoma: Functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and v

• 基底膜による上皮組織の形成および再生の制御機構
• 細胞外基質によるがん細胞の機能制御機構
• 糖鎖機能の統合的把握:グライコミクス
• シアル酸による細胞機能制御の分子機構の解明

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