Tohoku Medical and Pharmaceutical University · Graduate School of Pharmaceutical Sciences · 講師

Research keywordsLC-MS/MS・薬学教育・Cytochrome P450 (CYP・用いた

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• Simultaneous analysis of drugs administered to lung transplanted patients using liquid chromatography tandem mass spectrometry for therapeutic drug monitoring
• Establishment of an analytical method for simultaneous quantitation of CDK4/6 inhibitors, aromatase inhibitors, and an estrogen receptor antagonist in human plasma using LC-ESI-MS/MS
• Shifting the linear range of the calibration curves for the quantification of oral molecular-targeted anticancer drugs and the active metabolite in human plasma using LC-ESI-MS/MS
• 培養細胞を用いた健康食品と医薬品との薬物相互作用の網羅的調査

• 薬局薬剤師による薬剤性ＱＴ延長症候群防止のための基盤研究
• 3次元培養法を用いたシトクロムP450を介した薬物相互作用評価
• 未知の薬物相互作用の解明を目指したCYP4F2活性への薬物の影響評価

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