Tohoku Medical and Pharmaceutical University · Graduate School of Pharmaceutical Sciences · 講師

Research keywords薬理学・疼痛・神経障害・アンジオテンシン・糖尿病

Research fieldsNeuroscience in general・薬理学

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• Involvement of p38 MAPK activation mediated through AT1 receptors on spinal astrocytes and neurons in angiotensin II- and III-induced nociceptive behavior in mice.
• ERK5 activity is required for nerve growth factor-induced neurite outgrowth and stabilization of tyrosine hydroxylase in PC12 cells.
• Spinal ADAM17 contributes to the pathogenesis of painful diabetic neuropathy in leptin receptor-deficient mice
• [Behavioral and Molecular Pharmacological Study of the Role of Angiotensin II in Spinal Pain Transmission].

• 糖尿病性神経障害性疼痛の解明と新規治療法の開発：脊髄アンジオテンシン系からの検討
• ２型糖尿病に伴う神経障害性疼痛の解明：脊髄アンジオテンシン系の関与と治療薬の開発
• 慢性疼痛における脊髄アンジオテンシン系の役割の解明：新規治療法の開発を目指して
• 難治性疼痛における脊髄アンジオテンシンII機構の解明と新規治療法の開発

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