Tohoku University · Graduate School of Life Sciences · 助教

Research keywordsmitochondrial DNA mutations・trans-mitochondrial mice・mitochondrial dynamics・respiration-deficient mice・glioma metabolism・autophagy・lysophagy・mitochondrial differentiation・deafness models

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• Mitochondria in Lung Cancer ProgressionMasafumi Noguchi, Keiko Iwata, Norihito Shintani, Atsuko Kasahara
• Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner.Naho Nomura, Chiaki Ito, Takako Ooshio, Yuko Tadokoro, Susumu Kohno, Masaya Ueno, Masahiko Kobayashi, Atsuko Kasahara, Yusuke Takase, Kenta Kurayoshi, Sha Si, Chiaki Takahashi, Masaaki Komatsu, Toru Yanagawa, Atsushi Hirao
• Granzyme B-induced mitochondrial ROS are required for apoptosisG. Jacquemin, D. Margiotta, A. Kasahara, E. Y. Bassoy, M. Walch, J. Thiery, J. Lieberman, D. Martinvalet
• Targeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation.Kenta Kurayoshi, Yusuke Takase, Masaya Ueno, Kumiko Ohta, Kyoko Fuse, Shuji Ikeda, Takayoshi Watanabe, Yuki Nishida, Shin-Ichi Horike, Kazuyoshi Hosomichi, Yuichi Ishikawa, Yuko Tadokoro, Masahiko Kobayashi, Atsuko Kasahara, Yongwei Jing, Mahmoud I Shoulkamy, Makiko Meguro-Horike, Kensuke Kojima, Hitoshi Kiyoi, Hiroshi Sugiyama, Hiroki Nagase, Atsushi Tajima, Atsushi Hirao

• 細胞運命決定におけるオルガネラ接触部位制御メカニズムの解明笠原 敦子
• がん幹細胞性におけるミトコンドリア動態の果たす役割を明らかにする笠原 敦子
• がん悪性化におけるミトコンドリア逆行性制御の解明笠原 敦子
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