Tohoku University · Graduate School of Life Sciences

Research keywordsSTING signaling・lysosomal microautophagy・recycling endosomes・trans-golgi network・Rab GTPases・ESCRT-mediated degradation・innate immune signaling・palmitoylation-dependent clustering・retrograde membrane traffic

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• Adenosine kinase and ADAL coordinate detoxification of modified adenosines to safeguard metabolism.Akiko Ogawa, Satoshi Watanabe, Iuliia Ozerova, Allen Yi-Lun Tsai, Yoshihiko Kuchitsu, Harrison Byron Chong, Tomoyoshi Kawakami, Jirio Fuse, Wei Han, Ryuhei Kudo, Tomoki Naito, Kota Sato, Toru Nakazawa, Yasunori Saheki, Akiyoshi Hirayama, Peter F Stadler, Mieko Arisawa, Kimi Araki, Liron Bar-Peled, Tomohiko Taguchi, Shinichiro Sawa, Kenji Inaba, Fan-Yan Wei
• The activity of disease-causative STING variants can be suppressed by wild-type STING through heterocomplex formationRuri Shindo*, Yoshihiko Kuchitsu*, Kojiro Mukai, Tomohiko Taguchi
• Cell biological insights into human STING variants.Shogo Koide, Eisuke Yumoto, Jun Nakayama, Shigeki Higashiyama, Yoshihiko Kuchitsu, Tomohiko Taguchi
• Comprehensive knockout analysis of the Rab family GTPases in epithelial cells.Yuta Homma, Riko Kinoshita, Yoshihiko Kuchitsu, Paulina S Wawro, Soujiro Marubashi, Mai E Oguchi, Morié Ishida, Naonobu Fujita, Mitsunori Fukuda

• STING小胞クラスターのミクロオートファジー分解機構朽津 芳彦
• グルタミン飢餓により誘導される新規リソソーム活性調節機構の解明朽津 芳彦

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