Tohoku University · Graduate School of Life Sciences

Research keywordsDNA修復・相同組換え・PROTAC・タンパク質分解・ユビキチン化

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• Single-molecule sorting reveals how ubiquitylation affects substrate recognition and activities of FBH1 helicaseTokiha Masuda-Ozawa, Trish Hoang, Yeon Soo Seo, Lin Feng Chen, Maria Spies
• siRNA-mediated gene knockdown via electroporation in hydrozoan jellyfish embryosTokiha Masuda-Ozawa, Sosuke Fujita, Ryotaro Nakamura, Hiroshi Watanabe, Erina Kuranaga, Yu ichiro Nakajima
• Analysis of DNA-binding sites on Mhr1, a yeast mitochondrial ATP-independent homologous pairing proteinTokiha Masuda, Feng Ling, Takehiko Shibata, Tsutomu Mikawa
• Indirect ubiquitination independent of endogenous ubiquitination machinery for targeted protein degradationTakafumi Furuhata, Kazuki Yoshida, Ryoka Fujita, Jotaro Miyamoto, Chiharu Moriyama, Tokiha Masuda-Ozawa, Hikaru Tsuchiya, Yasushi Saeki, Akimitsu Okamoto

• 転写因子を標的とした新規プロテインノックダウン法の開発小澤 ときは
• 神経変性疾患の原因凝集性タンパク質を分解する新規分解薬の創製小澤 ときは

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