Tohoku University · Faculty of Agriculture / Graduate School of Agriculture · 准教授

Research keywordsDNA double-strand breaks・rDNA damage relocation・nuclear pore biology・ribosome biogenesis・yeast genetics・histone H2A.Z evolution・SUMO-mediated repair

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• Nuclear pore links Fob1-dependent rDNA damage relocation to lifespan control.Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome
• Yeast Rrp14p is a nucleolar protein involved in both ribosome biogenesis and cell polarity.Hiroko Yamada, Chihiro Horigome, Takafumi Okada, Chiharu Shirai, Keiko Mizuta
• A ribosome assembly factor Ebp2p, the yeast homolog of EBNA1-binding protein 2, is involved in the secretory response.Chihiro Horigome, Takafumi Okada, Kana Matsuki, Keiko Mizuta
• Rejuvenation of ribosomal RNA gene repeats at the nuclear poreChihiro Horigome, Takehiko Kobayashi

• リボソームRNA遺伝子の核膜結合と不等分配に関する研究2019 · 2019年12月 ～ 2020年11月
• 細胞の老化と若返りを支配するリボソームRNA遺伝子の不等分配に関する研究堀籠 智洋
• DNA相同組換え修復におけるホモロジーサーチの動態解明堀籠 智洋
• 細胞核構造によるゲノム安定化と老化抑制の機構解明堀籠 智洋

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