Tohoku University · Faculty of Pharmaceutical Sciences / Graduate School of Pharmaceutical Sciences · 教授

Research keywordsfungal secondary metabolites・epigenetic activation・polyketides・triterpenes・glandular trichomes・natural products chemistry・ribosomal peptide biosynthesis・anti-inflammatory sesquiterpenoids

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• Discovery of a Fungal HR-PKS Cluster Encoding Biosynthetic Pathways for Macrolides with Two Distinct Ring Sizes.Yi Li, Yohei Morishita, Akihiro Sugawara, Ashaimaa Y Moussa, Ahmed M Elissawy, Abdel Nasser B Singab, Taro Ozaki, Teigo Asai
• Synthetic Biology-Based Discovery of Diterpenoid Pyrones from the Genome of Eupenicillium shearii.Yohei Morishita, Kento Tsukada, Kazuma Murakami, Kazuhiro Irie, Teigo Asai
• Histone deacetylase inhibitor induced the production of three novel prenylated tryptophan analogs in the entomopathogenic fungus, Torrubiella luteorostrataTeigo Asai, Takashi Yamamoto, Yoshiteru Oshima
• 2-Acety-1-(3-glycosyloxyoctadecanoyl)glycerol and dammarane triterpenes in the exudates from glandular trichome-like secretory organs on the stipules and leaves of Cerasus yedoensisTeigo Asai, Yoshinori Fujimoto

• 糸状菌未開拓マクロライド生合成経路の再構築と再設計による新規抗生物質シーズの開拓浅井 禎吾
• 新規生合成マシナリー開拓を志向した未利用遺伝子活性化による天然物構造多様性の創出浅井 禎吾
• 合成生物学的手法を基盤とする活性天然物の構造展開研究浅井 禎吾
• エピジェネティックな遺伝子発現制御を利用した新規有用天然物の創出法の開発浅井 禎吾

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