Tohoku University · Center for Future Medicine Creation · 講師

Research keywordstRNA acetylation・translation fidelity・snRNA processing・cryo-EM structures・toxin-antitoxin complexes・RNA modification enzymes

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• Translocation and Rotation of tRNA during Template-Independent RNA Polymerization by tRNA Nucleotidyltransferase
• The Sam68 nuclear body is composed of two RNase-sensitive substructures joined by the adaptor HNRNPL
• Structures of the first and second double-stranded RNA-binding domains of human TAR RNA-binding protein
• Molecular insights into replication initiation by Qβ replicase using ribosomal protein S1.

• ヒトTUT1によるRNAポリウリジル化の分子構造基盤
• 酸化ストレスにより活性化されるポリA付加酵素の構造機能解析
• ADPリボシル化酵素PARP7による自然免疫制御の分子構造基盤

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