Tohoku University · Faculty of Pharmaceutical Sciences / Graduate School of Pharmaceutical Sciences

Research keywords腎毒性・ヒ素・セレノプロテインP・シスプラチン

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• Cisplatin caused highly delayed cytotoxicity in the immortalized cells derived from S3 segment of mouse kidney proximal tubulesHiroki Taguchi, Daigo Sumi, Ayumi Uemura, Kanako Matsumoto, Hitomi Fujishiro
• Arsenite increases sialic acid levels on the cellular surface through the inhibition of sialidase activity.Hiroki Taguchi, Hitomi Fujishiro, Daigo Sumi
• Phosphorus and potassium distributions in the kidneys of mice administered with renal tubular invasion heavy metals by micro-PIXEShino Homma-Takeda, Hitomi Fujishiro, Izumi Tanaka, Haruko Yakumaru, Hiroki Taguchi, Kyoko Ayama, Masakazu Oikawa, Seiichiro Himeno
• Ferroptosis is involved in cisplatin sensitivity of the S3 segment of immortalized proximal tubule cells.Hiroki Taguchi, Daigo Sumi, Seiichiro Himeno, Hitomi Fujishiro

• リソソーム酸性化と白金架橋形成を標的とした新規シスプラチン腎障害予防薬の創出田口 央基
• セレノプロテインPを用いたシスプラチン腎障害防御機構の解明と新規治療薬への応用田口 央基

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