Tohoku University · Faculty of Pharmaceutical Sciences / Graduate School of Pharmaceutical Sciences · 准教授

Research keywordsカルシウムシグナル・認知/精神疾患・認知症・Neuroscience・Internal・medicine・Long-term・potentiation

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• Scabronine G methyl ester improves memory-related behavior and enhances hippocampal cell proliferation and long-term potentiation via the BDNF-CREB pathway in olfactory bulbectomized mice.Osamu Nakagawasai, Lin Jia-Rong, Takayo Odaira, Kohei Takahashi, Wataru Nemoto, Shigeki Moriguchi, Yasushi Yabuki, Yu Kobayakawa, Kohji Fukunaga, Masahisa Nakada, Koichi Tan-No
• Rivastigmine restores 5-HT1A receptor levels in the hippocampus of olfactory bulbectomized mice.Muhammad Rashedul Islam, Shigeki Moriguchi, Hideaki Tagashira, Kohji Fukunaga
• A novel cognitive enhancer, ZSET1446/ST101, promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbectomized miceNorifumi Shioda, Yui Yamamoto, Feng Han, Shigeki Moriguchi, Yoshimasa Yamaguchi, Masataka Hino, Kohji Fukunaga
• Pharmacological study on Alzheimer's drugs targeting for calcium/calmodulin-dependent protein kinase II.Shigeki Moriguchi

• カルシウム恒常性破綻による認知・精神機能障害の病態機序解明2004 · 2004年4月 ～ 継続中
• カルシウムシグナル賦活化によるアルツハイマー病創薬研究2001 · 2001年9月 ～ 継続中
• 統合失調症の脳脆弱性における脂肪酸結合蛋白質の役割福永 浩司, 森口 茂樹
• Kir6.2チャネル阻害作用を標的としたアルツハイマー病創薬研究森口 茂樹, 福永 浩司

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