Tokai University · Graduate School of Health Sciences / Faculty of Health Sciences · 准教授

Research keywords生活習慣病・がん・鉄の代謝・老年性疾患

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• Iron-induced transferrin receptor-1 mRNA destabilization: A response to "Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation".
• Transplantation of Fibroblast Sheets with Blood Mononuclear Cell Culture Exerts Cardioprotective Effects by Enhancing Anti-Inflammation and Vasculogenic Potential in Rat Experimental Autoimmune Myocarditis Model.
• Regulation of transferrin receptor-1 mRNA by the interplay between IRE-binding proteins and miR-7/miR-141 in the 3'-IRE stem-loops.
• 酸化ストレスと老化のバイオロジー

• miRNAに着目したPanNETの薬剤耐性獲得メカニズムの解明と革新的治療法の開発
• 転写因子MXL-3による酸化ストレス応答と栄養シグナルの統合機構の解明
• がん細胞内の鉄環境を標的としたがん治療戦略の構築
• 鉄の細胞内制御システムを標的とした新規抗がん剤の開発

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