Tokai University · Faculty of International Studies · 助教

Research keywordsreactive oxygen species・mitogen activated protein kinases・endothelial cells・mitochondria・toxicology・antithrombotic agents

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• C-type lectin-like receptor (CLEC)-2, the ligand of podoplanin, induces morphological changes in podocytes.
• A pull-down and slot blot-based screening system for inhibitor compounds of the podoplanin-CLEC-2 interaction.
• Activation of the mitochondrial caspase cascade in the absence of protein synthesis does not require c-Jun N-terminal kinase.
• Cell signalling by oxidized lipids and the role of reactive oxygen species in the endothelium

• 次世代型神経筋電気刺激法による理学療法の代替効果の検証
• 高齢者敗血症におけるマクロファージの機能障害の機序解明と治療への応用
• 敗血症感染原因菌に対する抗体カクテル療法の確立と治療への応用
• CLEC-2とGPVIを標的とした新規抗血小板薬の開発とその適応症の探索

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