Tokai University · Graduate School of Biological Sciences

Research keywordsatherosclerosis・life style-related diseases・metabolic syndrome・monoclonal antibody・メイラード反応・メタボリックシンドローム・モノクローナル抗体・動脈硬化・生活習慣病・AGEs

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• Advanced glycation end product (AGE) accumulation on Bruch's membrane: Links to age-related RPE dysfunction
• Macrophage scavenger receptor mediates endocytosis of proteins modified with Glycolaldehyde, a reactive intermediate for advanced glycation end products
• AGEの測定法と問題点
• Comparison of the ligand activity to scavenger receptors between highly- and mildly-modified AGE-proteins

• Investigation of the pathogenesis of life style-related diseases and its prevention by natural compounds.
• 生活習慣病発症機構の解明と天然物を用いたその予防法の検討
• アルコール毒性の解明とその食品成分による予防
• AGEs特異抗体を用いた糖代謝異常の早期検出とその治療に関する研究

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