Tokushima University · Faculty of Dentistry · 助教

Research keywordsnon-coding RNAs、細胞外小胞、代謝、肥満、慢性炎症、食品機能、多能性幹細胞

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• Carnosic acid attenuates cartilage degeneration through induction of heme oxygenase-1 in human articular chondrocytes.
• miR-26a deficiency is associated with bone loss and reduced muscle strength but does not affect severity of cartilage damage in osteoarthritis.
• Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
• Transgenic mice specifically expressing amphiregulin in white adipose tissue showed less adipose tissue mass.

• 肥満白色脂肪組織の慢性炎症，および大腸炎の可視化を目指した新規動物評価法の構築
• microRNAに着目した肥満による変形性膝関節症の発症機構の解明
• 組織線維化に関わるmicroRNA-26aの機能解明、および線維化治療への展開
• 変形性関節症における老化細胞エクソソームの解明と機械学習を利用した治療薬の探索

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