Tokushima University · Faculty of Pharmaceutical Sciences · 助教

Research keywordsbrain microvascular endothelial cell・microsomal prostaglandin e synthase-1・transport characteristics of placenta-derived・e in hela cells・relevance to placenta-to-maternal tissue・via synaptic protein phosphorylation

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• Hypoxia suppresses glucose-induced increases in collective cell migration in vascular endothelial cell monolayers
• Polarized secretion of extracellular vesicles from the placenta to maternal and fetal bloodstreams in rats
• In vitro characterization of taurine transport using the human brain microvascular endothelial cell line as a human blood-brain barrier model.
• The Neurexin1β Histidine-Rich Domain Is Involved in Excitatory Presynaptic Organization and Short-Term Plasticity

• 胎盤-脳連関に立脚した胎盤エクソソームの血液脳関門透過機構と脳細胞送達性の解明
• 内在性ウイルスエンベロープを介したエクソソーム輸送機構に基づく胎盤への薬物送達
• 血液循環-胎盤分泌膜小胞を主軸としたヒト胎盤関門輸送機能の個別化予測法の基盤構築
• 胎盤由来エクソソームを中核とする胎盤関門機能予測

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