Tokushima University · Faculty of Pharmaceutical Sciences · 教授

Research keywordsNucleic Acid Chemistry・核酸有機化学

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• Synthesis and properties of a novel nucleoside derivative possessing a 2,3,5,6-tetraazabenzo[cd]azulene skeleton
• Synthesis and characterization of oligodeoxynucleotides containing a novel tetraazabenzo[cd]azulene:naphthyridine base pair
• A catch and release strategy towards HPLC-free purification of synthetic oligonucleotides using a phosphoramidite unit possessing a photocleavable azide linker
• RNAを標的とする低分子創薬の進展

• 新規抗腫瘍性ヌクレオシドDMDCおよびCNDACの作用機序の解明
• Chemical and Enzymatic Synthesis of 4'-thioRNA and Its Biological Application
• Design and Synthesis of Artificial Nucleosides and their Applications to Functional Molecules
• Pd触媒を用いた新規環状2本鎖DNAの合成と機能性デコイ分子の創製

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